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La Organizacin Mundial de la Salud (OMS) emiti una recomendacin histrica a favor del uso de tres medicamentos anlogos del GLP-1 semaglutida, liraglutida y tirzepatida para tratar la obesidad, una enfermedad que afecta a mil millones de personas en el mundo y que podra duplicarse en cinco aos

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This state-of-the-art narrative review synthesizes current evidence from clinical trials, pharmacovigilance databases, and real-world cohorts to provide a comprehensive evaluation of the safety and tolerability of GLP-1RAs and tirzepatide