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There is also a chance that both medications could cause changes in mood

While it significantly reduces appetite, full suppression may not be achievable for everyone

Your healthcare provider will evaluate your health history and risk for thyroid tumors to decide if semaglutide is safe for you

Once the pen is opened, even if it was previously refrigerated, the storage instructions change to room temperature with a much shorter lifespan, as detailed in the How long can semaglutide stay out of the fridge? section

A useful way to put the results into perspective is to compare retatrutide to other weight loss medications

Supplementary Materials Data Availability Statement All data are available at the corresponding author upon request.