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Furthermore, 100% of patients treated with GLP-1RAs lost more than 5% of body weight, compared to 36% with conventional weight loss strategies (10)
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(2016) showed that in addition to D198 2.68b A, D198 2.68b N and D198 2.68b E mutants also diminished GLP-1 and exendin-4 affinity and GLP-1 potency
