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Overall, these findings raise concerns about GLP-1 RA use in patients with reduced LVEF

Probiotic effects depend on consistent colonization over weeks and months, not on individual doses
doi: 10.1016/j.molmet.2024.101880 244 Re CecconiADBaroneMFortiMLunardiMCagnottoASalmonaMet al

This is supported by cell-killing assays which indicate increased lysis of NK cell-sensitive lines after GLP-1 treatment, alongside heightened production of IFN- and granzyme B [173]

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