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Initiation always starts with the lowest dose, then increments to minimise gastrointestinal side effects such as nausea

FDA approval was applied in December 2016, and in October 2017 FDA Advisory Committee voted 16-0 in favor

They ensure safe, effective treatment through careful assessment, precise dosing, and continuous monitoring

Considering both the rapid adoption of GLP-1RAs and the demonstrated health benefits of net reductions in alcohol use, 53 GLP-1RArelated reductions in consumptionwhen considered at large scalecould lead to improved health outcomes that are not currently appreciated

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