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Ozempic label, AccessFDA Gastrointestinal adverse events associated with semaglutide: A pharmacovigilance study based on FDA adverse event reporting system, Frontiers in Public Health (2022) Gastrointestinal tolerability of onceweekly semaglutide 2.4 mg in adults with overweight or obesity, and the relationship between gastrointestinal adverse events and weight loss, Diabetes, Obesity, and Metabolism (2021) Risk of gastrointestinal adverse events associated with glucagon-like peptide-1 receptor agonists for weight loss, JAMA Network (2023) Constipation, Penn State College Medicine Foods for constipation, Johns Hopkins Medicine Exercise therapy in patients with constipation: A systematic review and meta-analysis of randomized controlled trials, Scandinavian Journal of Gastroenterology (2019) Bowel retraining, National Library of Medicine (2022) Concerned about constipation

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This class of drugs was initially developed in the late 1990s and early 2000s, with exenatide, the first twice-daily GLP-1 approved for T2D in 2005

Prescription Care If appropriate, your clinician might prescribe FDA-approved medications like Ozempic, Wegovy or other GLP-1s

Patients should be aware of the risk of dehydration from gastrointestinal side effects, which could potentially lead to acute kidney injury

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