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Long-term adherence is essential to realizing the full therapeutic potential of GLP-1s, yet behavioral factors (such as reaching personal weight goals or perceived social stigma) and systemic issues (like high out-of-pocket costs and fragmented care) disproportionately affect obesity patients

This study is based on data from the Clinical Practice Research Datalink obtained under license from the UK Medicines and Healthcare products Regulatory Agency

Purpose of Review Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are used by increasing numbers of patients, but may adversely affect the safety of endoscopic procedures, due to their association with decreased gastrointestinal motility

While weight loss itself often improves anxiety symptoms, emerging research suggests the medication may have direct effects on stress pathways independent of body composition changes