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The absence of leg cramps from official labeling does not definitively rule out a connection, as post-marketing experience sometimes reveals adverse effects not detected in pre-approval trials due to sample size limitations, duration of follow-up, or patient population differences

GIP Receptor: Enhances insulin secretion and may modulate lipid metabolism

[DOI] [PubMed] [Google Scholar] 5.Hyperthyroidism and other causes of thyrotoxicosis: management guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists

It also highlights the need for pharmaceutical manufacturers to be more accountable when severe side effects arent adequately disclosed

Glucagon-like peptide-1 receptor agonists for treatment of nonalcoholic steatohepatitis: new insights from subcutaneous semaglutide

But because most dietary fat is in the form of triglycerides, if you unknowingly eat any carbohydrates, your body can switch back to processing carbs for energy leaving you with elevated triglyceride levels
