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That is reassuring at a population level

Cavallini, G., Ferraretti, A

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Microbial-host interplay in TMAO synthesis and metabolism TMAO originates from dietary precursors metabolized through a tightly coordinated interplay between gut microbiota and host hepatic enzymes (50)

Aging is associated with a shift toward more pro-inflammatory oxylipin species, which may impair microvascular perfusion and attenuate anabolic responsiveness (96)

Direct scavenging of free radicals, suppression of oxidative processes, repair of oxidative damage, upregulation of antioxidant enzyme production, and stabilization of cell membranes are a few examples of these strategies (8285)